General description

Mucolytic agent and thiol-based antioxidant that has a protective effect against oxygen free radicals in early septic shock. Increases cellular pools of free-radical scavengers. Inhibitor of HIV replication. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.

A mucolytic agent and thio-based antioxidant. Increases the cellular pool of free-radical scavengers. Inhibits HIV replication. Prevents apoptotic death of neuronal cells. Antidote for acetaminophen poisoning. May serve as a substrate for microsomal glutathione transferase. Induces apoptosis in human and rat smooth muscle cells.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Ortolani, O., et al. 2000. Am. J. Respir. Crit. Care Med. 161, 1907.Tsai, J.C., et al. 1996. J. Biol. Chem. 271, 3667.Ferrari, G., et al. 1995. J. Neurosci.15, 2857.Weinander, R., et al. 1994. J. Biol. Chem.269, 71.

Packaging

Packaged under inert gas

5 g in Plastic ampoule

Reconstitution

Following reconstitution aliquot and freeze (-20°C). Aqueous stock solutions are stable for up to 1 month at -20°C.

Warning

Toxicity: Standard Handling (A)